These are the 50 counties with the greatest decrease in personal income from 2005 to 2006:
| Rank | County | State | Income 2005 | Income 2006 | $ Change | % Change |
| 1 | Slope | ND | $24,640 | $13,885 | -$10,755 | -43.6% |
| 2 | Campbell | SD | $28,968 | $19,971 | -$8,997 | -31.1% |
| 3 | Ziebach | SD | $16,314 | $11,381 | -$4,933 | -30.2% |
| 4 | Hyde | SD | $29,571 | $21,609 | -$7,962 | -26.9% |
| 5 | Lynn | TX | $29,625 | $22,013 | -$7,612 | -25.7% |
| 6 | Sherman | TX | $49,610 | $36,938 | -$12,672 | -25.5% |
| 7 | Borden | TX | $31,506 | $23,695 | -$7,811 | -24.8% |
| 8 | Sully | SD | $48,380 | $36,822 | -$11,558 | -23.9% |
| 9 | Harding | SD | $27,954 | $21,640 | -$6,314 | -22.6% |
| 10 | Faulk | SD | $33,361 | $26,230 | -$7,131 | -21.4% |
| 11 | Kiowa | CO | $33,538 | $26,516 | -$7,022 | -20.9% |
| 12 | Emmons | ND | $28,012 | $22,317 | -$5,695 | -20.3% |
| 13 | Logan | ND | $36,035 | $28,832 | -$7,203 | -20.0% |
| 14 | Haakon | SD | $38,932 | $31,254 | -$7,678 | -19.7% |
| 15 | Hand | SD | $34,976 | $28,278 | -$6,698 | -19.2% |
| 16 | Jackson | SD | $19,509 | $15,846 | -$3,663 | -18.8% |
| 17 | Jones | SD | $28,126 | $22,857 | -$5,269 | -18.7% |
| 18 | Dunn | ND | $27,528 | $22,691 | -$4,837 | -17.6% |
| 19 | Buffalo | SD | $15,073 | $12,471 | -$2,602 | -17.3% |
| 20 | Swisher | TX | $29,886 | $24,760 | -$5,126 | -17.2% |
| 21 | Sheridan | ND | $28,186 | $23,469 | -$4,717 | -16.7% |
| 22 | Hettinger | ND | $29,785 | $24,835 | -$4,950 | -16.6% |
| 23 | Castro | TX | $40,478 | $33,866 | -$6,612 | -16.3% |
| 24 | Carter | MT | $26,715 | $22,418 | -$4,297 | -16.1% |
| 25 | McPherson | SD | $27,432 | $23,130 | -$4,302 | -15.7% |
| 26 | Perkins | SD | $28,124 | $24,006 | -$4,118 | -14.6% |
| 27 | Renville | ND | $33,305 | $28,533 | -$4,772 | -14.3% |
| 28 | Gove | KS | $28,896 | $24,877 | -$4,019 | -13.9% |
| 29 | Edmunds | SD | $38,658 | $33,289 | -$5,369 | -13.9% |
| 30 | McIntosh | ND | $31,396 | $27,156 | -$4,240 | -13.5% |
| 31 | Hamilton | KS | $30,607 | $26,561 | -$4,046 | -13.2% |
| 32 | Burke | ND | $34,685 | $30,134 | -$4,551 | -13.1% |
| 33 | Beaver | UT | $28,793 | $25,017 | -$3,776 | -13.1% |
| 34 | Wells | ND | $33,803 | $29,474 | -$4,329 | -12.8% |
| 35 | Floyd | TX | $29,687 | $25,942 | -$3,745 | -12.6% |
| 36 | Scurry | TX | $32,690 | $28,601 | -$4,089 | -12.5% |
| 37 | Garfield | MT | $29,696 | $25,998 | -$3,698 | -12.5% |
| 38 | Hickman | KY | $43,964 | $38,961 | -$5,003 | -11.4% |
| 39 | Lyman | SD | $23,330 | $20,780 | -$2,550 | -10.9% |
| 40 | Clark | SD | $30,593 | $27,343 | -$3,250 | -10.6% |
| 41 | Eddy | ND | $28,109 | $25,158 | -$2,951 | -10.5% |
| 42 | Sheridan | KS | $34,952 | $31,328 | -$3,624 | -10.4% |
| 43 | Loup | NE | $10,172 | $9,140 | -$1,032 | -10.1% |
| 44 | Banner | NE | $26,063 | $23,434 | -$2,629 | -10.1% |
| 45 | Corson | SD | $20,822 | $18,731 | -$2,091 | -10.0% |
| 46 | Kidder | ND | $28,808 | $26,052 | -$2,756 | -9.6% |
| 47 | Tripp | SD | $27,884 | $25,234 | -$2,650 | -9.5% |
| 48 | Divide | ND | $30,980 | $28,052 | -$2,928 | -9.5% |
| 49 | Baca | CO | $28,317 | $25,761 | -$2,556 | -9.0% |
| 50 | Harding | NM | $19,571 | $17,849 | -$1,722 | -8.8% |